Aesthetic Treatments For The GLP-1 Effect

GLP-1 medications such as Ozempic and Wegovy (semaglutide), and Mounjaro (tirzepatide) have had a major surge in popularity, with their original effects having been designed to treat diabetes no longer being the sole reason for prescription. Now, the capabilities of these ground-breaking medications have extended to weight management and overall weight loss. With their appetite-regulating benefits, patients are able to rapidly lose residual stubborn weight, without the need for more invasive means of surgery like gastric by-passes. 

However, as individuals go through the process of what’s often very rapid and significant weight reduction, they are often met with a new set of aesthetic concerns. These can include skin laxity, a change in the skin’s texture, and a reduction of overall firmness.

As a result, a secondary layer to the weight loss process has surfaced: the Ozempic makeover. Along with losing weight, patients are seeking to refine and rebuild their bodies. This has led to a sharp increase in demand for advanced aesthetic solutions that can support the skin and tissue changes that follow GLP-1 use. InMode’s technology was designed to alleviate many of these concerns in the same minimally invasive means as Ozempic. 

Why Skin Laxity Develops After Weight Loss

The skin is flexible and, naturally, can adjust and recover from weight loss. However, due to a combination of factors, including the fact that Ozempic often results in rapid weight loss, the look and feel of the skin changes. Along with the speed at which people lose weight, the collagen content of the skin is also often either compromised or insufficient. As we age, our bodies naturally produce less collagen and elastin, two proteins that are essential for youthful looking skin, but they’re also responsible for supporting the skin’s structure. When there’s less collagen and elastin in the skin overall and the skin has been stretched over time, then the underlying fat volume reduces, and the skin may not rebound fully, leading to sagging, folds, or hollowed areas. 

The loss of fat volume can impact the skin’s structure anywhere on the body, though the most common areas of concern are typically the face, neck, arms, abdomen, and thighs. While Ozempic/Mounjaro can be a wonderful option for those looking to feel more confident within themselves, the overall result isn’t always aligned with a patient’s hopes of looking and feeling better. In these cases, aesthetic improvement becomes less about aesthetics alone and more about completion, supporting the body through every phase of transformation. 

InMode’s advanced suite of technologies can transform, tone and tighten the loose skin, supporting the body’s ability to create more collagen, all through non-invasive and minimally invasive means. With the applicators from IgniteRF, patients can complete their dream body transformations without intensive surgical means. 

How InMode Technologies Support Skin and Tissue Recovery

InMode’s suite of medical aesthetic devices delivers non-invasive and minimally invasive treatments that help rebuild, recontour, and revitalise the skin at every level, from the epidermis through to the deep, sub-dermal later. For patients coming off GLP-1 medications or actively managing ongoing weight reduction, these technologies offer an advanced and clinically proven approach to improving skin texture and tone. 

Morpheus8: Deep Dermal Remodelling for Refined Skin Quality

Morpheus8 is InMode’s premier, award-winning device that blends fractional RF microneedling with bipolar radiofrequency energy, delivering targeted heating and coagulation deep within the dermis. With a range of microneedle attachment tips, Morpheus8 can treat the superficial layer of the epidermis at just a 0.5mm depth, through to the 8mm including the heat profile into the deeper layers of the skin’s tissue with the Body tip. By targeting the Fibro-Septal Network (FSN), the scaffold structure that connects the skin to deeper tissues such as muscle and fascia and holds it together, it promotes collagen production, remodels existing collagen and as a result, restructures and enhances tissue firmness. This makes it the ideal choice in addressing sagging skin, fine lines, and surface irregularities caused by weight-related volume loss.

The device delivers precise levels of therapeutic heating energy, encouraging skin revitalisation from within - without the need for surgery. This makes it a powerful choice for both facial and body rejuvenation.

QuantumRF: Contouring and Sculpting with Purpose

QuantumRF provides a unique minimally invasive, non-aspirational solution for patients who require more focused contouring and sculpting after rapid body composition changes without the requirement for surgery. Its subdermal RF technology treats tissue at multiple depths, stimulating collagen synthesis while simultaneously remodelling fat and connective tissue. The result is firmer, smoother skin and improved definition in areas that may appear deflated or loose after weight loss, providing skin tightening that no non-invasive products can provide. With two applicators, one designed for the more delicate areas and finer contours around the face and neck, and one for larger areas of the body, it offers a more customised approach to face and body contouring. 

This technology supports patients who want to restore tone and reduce the visible effects of excess skin without surgery, downtime or incisions.

Collagen Rebuilding as a Long-Term Strategy

All InMode technologies, including Morpheus8 and QuantumRF, were created with the principle that patients should be able to treat their transformations comprehensively, addressing the root cause of skin laxity while also improving the tone with every treatment. By targeting the Fibro-Septal Network, and increasing collagen and elastin production, these procedures do more than mask the effects of weight loss. Instead, they actively rebuild the dermal foundation for improved resilience and tone for a long-lasting effect, without the need for surgical intervention.

Treatments are typically performed as part of a tailored program. This accounts for factors like the individual’s ongoing weight loss goals, their areas of concern, and the condition of their skin. Providers can deliver transformative results, with every session delivering a noticeable improvement. Patients can expect to see consistent and positive changes in firmness, texture, and skin quality, contributing to their overall journey with GLP-1 medications. 

Meeting the Needs of Today’s Aesthetic Patient

The impact of GLP-1 medications is redefining aesthetic care. As more individuals reach their weight goals, the demand for appearance refinement, skin health optimisation, and body sculpting is only growing. Clinics that offer professional-grade procedures from InMode are equipped to support this shift with innovative, technology designed for real, consistent results.

Whether it’s restoring skin tone, remodelling contours, or enhancing overall appearance, InMode’s RF-based platforms are uniquely suited to address the aesthetic outcomes associated with weight loss - and to help patients look as confident as they feel.

To learn more or book a demo of our innovative technologies, contact us today and become a part of our Australian network of InMode providers.