Clinical Papers
Clinical Papers
on Dec 09 2021
Diastasis of recti abdominis muscle (DRAM) is a common condition occurring postpartum and thought to be a cause for back pain and pelvic instability. Electrical muscle stimulation (EMS) had been used in abdominal muscle rehabilitation in combination with exercises in DRAM. This study looks at the effect of EMS in treating DRAM in comparison to a control group receiving no treatment.
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Clinical Papers
on Dec 09 2021
The growing demand for non-surgical, non-invasive procedures for fat and circumference reduction and for cellulite treatments has led to the development of various energy-based technologies. Bi-polar radiofrequency (RF) technology combined with additional technologies, such as vacuum, massage or infrared (IR) light is widely used in various body contouring treatments in the medical aesthetic market. The current study is based on a retrospective efficacy analysis of an RF device, combining two RF modalities, coupled with suction.
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Clinical Papers
Late to the Party? Pyroptosis Becomes a New Mechanism of Cell Death for Adipocytes
on Nov 02 2021
For many years, medical practitioners have thought that cells die in one of only two ways: Either necrotic cells die violently when their outer membrane ruptures, or cells undergo programmed silent cell death through a mechanism called apoptosis. In 2001 Cookson and Brennan published an article in Trends in Microbiology describing a new means of cell death that occurs usually within the context of an infectious process called pyroptosis. This method of cell death exists in a continuum between the opposite processes of necrosis and apoptosis, and it exhibits characteristics of both. Pyroptosis is caspase mediated, but its initiator is caspase-1 instead of caspase-2, -8, -9, and -10, which initiate apoptosis. Because the full pyroptotic process takes time, the severe swelling that characterizes tissue response to necrosis is absent. Pyroptotic cell death is not totally silent, however—lysosomal exocytosis is also a marker; therefore varying degrees of inflammation can be seen with this mechanism.
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Clinical Papers
The Basic Science of Radiofrequency-Based Devices
on Mar 09 2021
This chapter outlines the basic science and specific principles of operation for radiofrequency (RF) technologies with a focus on minimally-invasive applications enhancing liposuction procedure. Before discussing the parameters, settings and techniques for radiofrequency-assisted lipolysis (RFAL) and fractional RF subdermal treatment, it is important to understand the fundamentals of the basic science of RF technologies and applications. The chapter accurately describes the physics of the processes occurring during RF-based treatment, and the factors affecting its safe and efficacious outcome. The discussion of RF-based devices will use terminology and definitions provided by FDA guidance for electrosurgical devices. Measurements and computer simulations conducted by the authors to illustrate importance of different parameters for the specific treatments of skin and subcutaneous fat are also presented.
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Clinical Papers
Aesthetic Applications of Radiofrequency: Lymphatic and Perfusion Assessment
on Aug 18 2020
The use of radiofrequency in aesthetics has increased in popularity since the early 2000s. To date, there have been limited studies investigating the effect of thermal energy secondary to radiofrequency treatment. The purpose of this study was to evaluate perfusion and lymphatic assessment tools pre and post bipolar and fractional radiofrequency treatment. A retrospective IRB-approved study was conducted between January 2019 and April 2019. Patients who were independently deemed appropriate candidates for radiofrequency soft tissue remodeling were evaluated. Diagnostic perfusion and lymphatic imaging obtained were reviewed using indocyanine green (SPY, Stryker) and optical coherence tomography (Vivosight OCT).
Clinical Papers
on Apr 28 2020
The finite element method was used, and experiments were performed to analyze the effect of different electrode spacings and power combinations on the electrical and thermal aspects of biological tissues during bipolar radiofrequency (RF) fat dissolution. Through these efforts, this study also attempted to develop a reasonable electrode spacing and power combination that can achieve fat dissolution effects, the RF energy of which will not thermally damage the tissue.
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Clinical Papers
on May 01 2017
While the field of noninvasive body contouring is booming, many patients still note a lesser result than they might achieve with a single session of liposuction or dermolipectomy. The duration of a noninvasive fat reduction treatment series can be daunting. Patients have questioned the worth of these procedures when the expected benefit is modest and the time they devote to the project is significant. An eight-patient mini-study was performed to see if two or three "megasessions" could be substituted for eight weekly sessions of bipolar radiofrequency based fat reduction treatments.
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Clinical Papers
on Nov 16 2016
Bipolar radiofrequency (RF) is capable of heating dermal collagen fibers and inducing skin tightening by collagen remodeling. Objective: To substantiate safety and improvement of skin laxity following skin heating with a novel temperature- and impedance-controlled non-invasive radiofrequency (RF) device by histological and biochemical evaluations
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Clinical Papers
on Jan 13 2016
Noninvasive fat reduction is claimed by many device manufacturers, but proof of efficacy has been difficult to establish. This prospective study was designed to measure the reduction of fat thickness and actual volume reduction in 20 female patients treated with an external radiofrequency (RF) device. This device combines RF heat, suction coupled vacuum, and oscillating electrical pulses that induce adipocyte death over time.
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